Ageing with HIV presents complex challenges. Older adults face higher risks of cardiovascular disease, cognitive decline, frailty, menopause symptoms, and other chronic conditions. These may occur earlier and be more severe among people with HIV, a phenomenon sometimes referred to as “accelerated aging.” Factors like chronic inflammation, immune dysregulation, and long-term ART use may contribute, but the biological, social, and gendered dimensions are still poorly understood.

The HEAL (HEalthy Ageing and HIV in Lesotho) study, nested within VICONEL, aims to fill this gap. Focusing especially on women, HEAL explores how ageing, HIV, gender, and socioeconomic factors interact to shape health outcomes. Using the framework of intersectionality, it examines both clinical indicators and lived experiences to understand what supports—or undermines—healthy ageing in this growing population.

Findings from HEAL will inform targeted interventions to meet the evolving needs of older people with HIV in Lesotho and beyond, ensuring they not only live longer, but also healthier and more dignified lives.

Principal Investigator

Anna Klicpera

Co-Investigators

Dr Mosa Tlahali (District Health Management Team Mokhotlong), Dr. Lebohang Sao-Chere (District Health Management Team Butha-Buthe), Dr. Tapiwa Tarumbiswa (Ministry of Health, Lesotho)